Lesson 1. Topic 1
The structure and principles of functioning of the immune system. Age immunology
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Age-specific features of the functioning of the immune system in children of all ages and the elderly. The concept of critical periods of the immune system.
Monocyte-macrophage system: functions, features, role in the formation and realization of the immune response.
Killing effect as a component of immunobiological surveillance. Basic types of killer cells, their function and properties.
Humoral factors of innate immunity.
Thymus: the main features of ontogeny and functioning.
The role of the T-link in the implementation of the immune response. Subpopulations of T lymphocytes. Major markers and clusters of differentiation.
B-cell immunity. Basic markers and features. Concepts of T-dependent and T-independent types of an immune response.
Immunoglobulins: structure, functions, classes. Characteristics of immune complexes and their role in the development of pathology.
Cytokines: classification, function and involvement in immune processes.
Structure and function of the major histocompatibility complex. The role of the HLA phenotype in the disease formation.